Convert the 24-hour oral opioid dose to a q4-hourly SC regime by:
E.g. MST 30mg PO BD
= Morphine sulphate 60mg PO over 24 hours
≈ Morphine sulphate 30mg SC over 24 hours
= Morphine sulphate 5mg SC q4-hourly.
Note: sometimes it may be necessary to round the dose of opioid to the nearest easily measurable dose.
Don’t forget to prescribe PRN medications also (see anticipatory one pager). Always review effectiveness of medications and titrate according to need. Specialist palliative care are always available to provide advice.
Health Library Ireland, Health Service Executive. Dr. Steevens' Hospital, Dublin 8. Tel: 01-6352555/8. Email: firstname.lastname@example.org